Investigation of the anti-anaemic activities of aqueous leaves extracts of Telfairia occidentalis, Spondias mombin, Ribes nigrum, Raw albumin and sugar combination and ferrous gluconate on experimental rats. The aqueous leaves extracts of T. occidentalis, S. mombin, R. nigrum were obtained by cold maceration and processed for 48 h, while albumin and sugar combination was mixed well by a mixer. Chloramphenicol model for experimental induction of anaemia in rats was utilized and the anti-anaemic activities was determined by measuring some haematological parameters of packed cell volume (PCV), haemeglobin count (Hb) and white blood cell count (WBC). The PCV and Hb levels of extracts treated rats were significantly (p < 0.05) increased compared to control group. The aqueous extract of T. occidentalis produced higher anti - anaemic activity compared to, R. nigrum, S. mombin, Raw albumin and sugar combination and ferrous gluconate but there was a small significant rise in the WBC level in all the extracts. The leaves extracts of T. occidentalis, R. nigrum, S. mombin and Raw Albumin and sugar combination has anti-anaemic activities, and this has revealed their uses as haematinics by many cultures.